"Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCov (Posted January 26, 2020)"
"We further compared the characteristics of the donors and their ACE2 expressing patterns. No association was detected between the ACE2-expressing cell number and the age or smoking status of donors. Of note, the 2 male donors have a higher ACE2-expressing cell ratio than all other 6 female donors (1.66% vs. 0.41% of all cells, P value=0.07, Mann Whitney Test). In addition, the distribution of ACE2 is also more widespread in male donors than females: at least 5 different types of cells in male lung express this receptor, while only 2~4 types of cells in female lung express the receptor. This result is highly consistent with the epidemic investigation showing that most of the confirmed 2019-nCov infected patients were men (30 vs. 11, by Jan 2, 2020).
We also noticed that the only Asian donor (male) has a much higher ACE2-expressing cell ratio than white and African American donors (2.50% vs. 0.47% of all cells). This might explain the observation that the new Coronavirus pandemic and previous SARS-Cov pandemic are concentrated in the Asian area."
2019-nCov kann anscheinend besonders gut bei männlichen Asiaten andocken. Das Problem an der Studie: Viel zu wenig Daten. Nichtsdestotrotz scheint die Realität die Vermutung zu bestätigen.
PS: Sollte dies stimmen, ist es unwahrscheinlich, dass der Virus aus einem chinesischen Biowaffenlabor entfleuchte.